My research interests are varied within orthopaedics and AI, and range from clinical studies to basic science and translational work. Innovation is at the core of it, and I'm always open to novel research ideas and collaborations.
One thread runs through all of it: does the intervention actually work, and how would we know? It began with cartilage biology and the paediatric hip, ran through trauma, infection and surgical education, took a detour through the history and art of medicine, and arrived at artificial intelligence, which is the same question again with a new object.
Building life changing research foundations. Barts Charity, 2019–2023. Ramachandran (CI), Bates P, Millington S, Hilton C, Kassam J
Innovate UK, 2018–2019. Ramachandran M (CI), Parvez N, Parvez S
Government of Malaysia programme grant, PDRA/PhD, 2012–2015. Chowdhury TT, Homandberg GA, Bader DL, Ramachandran M (Co-I)
Barts and The London Charity, 2014–2016. Ramachandran M (CI), Coggings D
Medical Research Council, 2014–2016. Knight M, Beales P, Chaple P, Mitchison H, Ramachandran M (Co-I)
Arthritis Research UK, 2015–2018. Dell'Accio F, Eldridge SE, Bertrand J, Sherwood J, Ramachandran M (Co-I)
Aarhus University, Denmark, 2012–2015. Ramachandran M (CI), Gottliebsen M, Rahbek O, Moller-Madsen B
Dunhill Medical Trust, 2014–2016. Lee D, Caton P, Heywood H, Ramachandran M (Co-I)
Arthritis Research UK, 2011–2013. Chowdhury TT, Ramachandran M (Co-I), Bader DL
QM Proof of Concept award, 2014–2016. Mata A, Ramachandran M (PI)
Joule Canadian Medical Association Grant. Jaremko J, Mansi C, Golan D, Ramachandran M (Co-I)
AO Foundation (C-type natriuretic peptide and mechanical loading in human cartilage); National Institute of Biological Standards Control (CNP in osteoarthritis and FAI); Aarhus University pump-priming (hip arthroscopy porcine model); DBI/MRC/EPSRC pump priming (anti-inflammatory effect of CNP)
Over 150 papers. Below is the shape of the work, with the papers I'd hand someone who wanted to understand it in an afternoon.
Chondrocyte homeostasis, mechanical signalling and the biology that decides whether a joint can repair itself.
Fracture healing, bisphosphonates, BMPs and the anabolic and catabolic responses in bone repair.
DDH, Perthes, slipped capital femoral epiphysis, and the young adult hip. Genetics, natural history, technique and outcome.
Including the UK FASHIoN randomised controlled trial, published in the Lancet.
Supracondylar fractures, non-accidental injury, elastic nailing, and whether guidelines change outcomes.
Paediatric bone and joint infection, septic arthritis and osteomyelitis.
The Ponseti method, congenital vertical talus, and what treatment costs the families who go through it.
The newest strand, and the one I now spend most of my non-clinical time on.
Whether surgeons are trained and assessed as well as we assume. Mostly, the answer has been no.
Where I learned what a claim looks like before there was evidence to check it. The Diagnosis of Art series with J.K. Aronson ran for years in the Journal of the Royal Society of Medicine.
Full list on Google Scholar and PubMed.
Medtech design and artificial intelligence.
Children's hip arthroscopy.
Postgraduate courses.
Paediatric hip and basic science.
Clinical studies, basic science, translational work, and the evaluation of AI where it meets real patients.
Get in touch